HIV-Associated Disseminated Emmonsiosis, Johannesburg, South Africa
نویسندگان
چکیده
Technical Appendix Table 1. Laboratory results at admission for 3 patients with HIV-associated disseminated emmonsiosis, Johannesburg, South Africa* Laboratory investigation Case 1 Case 2 Case 3 Reference range CD4 count 5 cells/μL 3 cells/μL 0 cells/μL 50–2010 cells/μL Leukocyte count 16.91 × 10/L 1.52 ×1 0/L 1.84 × 10/L 4.00–10.00 × 10/L Hemoglobin 8.7 g/dL 11.7 g/dL 7.8 g/dL 14.3–18.3 g/dL Mean cell volume 91 fL 90 fL 87.6 fL 83–101 fL Platelets 523 × 10/L 74 × 10/L 122 × 10/L 150–400 × 10/L Sodium 121 mmol/L 111 mmol/L 128 mmol/L 136–145 mmol/L Potassium 3.7 mmol/L 4 mmol/L 4.8 mmol/L 3.5–5.1 mmol/L Chloride 77 mmol/L 79 mmol/L 101 mmol/L 98–107mmol/L Bicarbonate 30 mmol/L 16 mmol/L 16 mmol/L 23–29 mmol/L Urea 31.4 mmol/L 5.5 mmol/L 4.8 mmol/L 2.1–7.1 mmol/L Creatinine 590 μmol/L 55 μmol/L 64 μmol/L 64–104 μmol/L Total bilirubin 5 μmol/L 12 μmol/L 7 μmol/L 5–21 μmol/L Conjugated bilirubin 3 μmol/L 9 μmol/L 5 μmol/L 0–3 μmol/L Total protein 51 g/L 56 g/L 46 g/L 60–78 g/L Albumin 11 g/L 22 g/L 13 g/L 35–52 g/L Alkaline phosphatase 400 U/L 301 U/L 131 U/L 40–120 U/L γ-glutamyl transpeptidase 396 U/L 228 U/L 92 U/L 0–60 U/L Alanine transaminase 37 U/L 53 U/L 40 U/L 10–40 U/L Aspartate transaminase 266 U/L 94 U/L 145 U/L 15–40 U/L Hepatitis A IgM antibody Neg Neg ND – Hepatitis B surface antigen Neg Neg ND – Hepatitis B core IgM antibody Neg Neg ND – Hepatitis C antibody Neg Neg ND – Cryptococcal serum antigen Neg Neg Neg – CSF polymorphonuclear cells 0 0† 0 0 CSF lymphocytes 0 0† 0 0 CSF erythrocytes 0 18† 30 0 *CD4, CD4+ T-cell; CSF, cerebrospinal fluid; ND, not done; Neg, negative; NG, no growth. †Lumbar puncture results reported are from a hospitalization in June 2013; meningeal disease was not suspected during the August 2013 hospitalization when the patient was diagnosed with emmonsiosis.
منابع مشابه
Prevalence and Risk Factors for Self-reported Sexually Transmitted Infections among Adults in the Diepsloot Informal Settlement, Johannesburg, South Africa
Tariro J Basera1,5, Simbarashe Takuva2,3, Keith Muloongo4, Ndumiso Tshuma4 and Peter S Nyasulu1,5* 1School of Health Sciences, Monash University, 144 Peter Road, Ruimsig, Johannesburg, South Africa 2Perinatal HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa 3Centre for HIV and...
متن کاملClinical Characteristics, Diagnosis, Management, and Outcomes of Disseminated Emmonsiosis: A Retrospective Case Series.
BACKGROUND We describe the geographic distribution, clinical characteristics, and management of patients with disease caused by Emmonsia sp., a novel dimorphic fungal pathogen recently described in South Africa. METHODS We performed a multicenter, retrospective chart review of laboratory-confirmed cases of emmonsiosis diagnosed across South Africa from January 2008 through February 2015. RE...
متن کاملChildren's daily travel to school in Johannesburg-Soweto, South Africa: geography and school choice in the Birth to Twenty cohort study
Children's daily travel to school in Johannesburg-Soweto, South Africa: geography and school choice in the Birth to Twenty cohort study Julia de Kadt, Shane A. Norris, Brahm Fleisch, Linda Richter & Seraphim Alvanides a Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesbur...
متن کاملFirst infant Mental Health Conference in Johannesburg, South Africa Dialogues in a Multidisciplinary Context
Research in sub-Saharan Africa has highlighted poor child development outcomes associated with deprivation (see Lancet special edition on child development, 2007). Early intervention is required in order to facilitate positive, long-lasting treatment effects. However, as is the case in many developing countries, funding in South Africa focuses on decreasing HIV infection and infant mortality ra...
متن کاملA case of emmonsiosis in an HIV-infected child
Opportunistic fungal infections can cause significant morbidity and mortality in immunocompromised patients. We describe a paediatric case of an unusual disseminated fungal infection. A three-year-old HIV-infected child with severe immunosuppression (CD4+ T-cell count 12 × 106/L) was admitted to hospital with pneumonia, gastroenteritis and herpes gingivostomatitis. Despite antibacterial and ant...
متن کامل